Tracing genomic instability in induced mesenchymal stromal cell manufacture: an integration-free transfection approach

Abstract Here we systematically investigated genomic alterations from the initiation of induced pluripotent stem (iPS) cell generation to induced mesenchymal stromal/stem cell differentiation.We observed a total of ten copy number alterations (CNAs) and five single-nucleotide variations (SNVs) during the phases of reprogramming, differentiation and

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Adapted yoga to improve physical function and health-related quality of life in physically-inactive older adults: a randomised controlled pilot trial

Abstract Background Yoga is a holistic therapy of expanding popularity, which has the potential to produce a range of physical, mental and social benefits.This trial evaluated the feasibility and effects of an adapted yoga programme on physical function and health-related quality of life in physically-inactive older adults.Methods In this randomise

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Using the bio-psycho-social-spiritual framework in holistic health and well-being: A case example of a community- and faith-based sports program

As in other parts of the world, copyright’s citizens are confronted with biological, mental, and social crises.Despite the fact that these issues can be interrelated, they are regularly studied and addressed separately.The bio-psycho-social (BPS) framework was offered as an alternative approach for care because of its assumption that in order to

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All superconducting tokamak: EAST

Abstract Experimental Advanced Superconducting Tokamak (EAST) was built to demonstrate high-power, long-pulse operations under fusion-relevant conditions, with major radius R = 1.9 m, minor radius a = 0.5 m, and design pulse length up to 1000s.It has an ITER-like D-shaped cross-section with two symmetric divertors at the top and bottom, accommodati

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